Five-fold lifespan extension in C. Elegans by combining mutants | KurzweilAI

Posted: December 22, 2013 by Wildcat in Uncategorized

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New research published published online in Cell Reports on December 12, 2013 (open access) with the nematode C. elegans suggests that combining mutants can lead to radical lifespan extension.

Scientists at the Buck Institute combined mutations in two pathways well known for lifespan extension and report a synergistic five-fold extension of longevity — these worms lived to the human equivalent of 400 to 500 years — introducing the possibility of combination therapy for aging and the maladies associated with it.

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