Posted: May 8, 2012 by Wildcat in Uncategorized
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S cientists have remotely activated genes inside living animals, a proof of concept that could one day lead to medical procedures in which patients’ genes are triggered on demand. The work, in which a team used radio waves to switch on engineered insulin-producing genes in mice, is published recently in Science. Jeffrey Friedman, a molecular geneticist at the Rockefeller University in New York and lead author of the study, says that in the short term, the results will lead to better tools to allow scientists to manipulate cells non-invasively. But with refinement, he thinks, clinical applications could also be possible. Friedman and his colleagues coated iron oxide nanoparticles with antibodies that bind to a modified version of the temperature-sensitive ion channel TRPV1, which sits on the surface of cells. (via 33rd Square | Researchers Use Radio Waves To Switch Genes On And Off)

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